STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
F7Coagulation factor VII. (526 aa)    
Predicted Functional Partners:
F3
Coagulation factor III, tissue factor.
    
 0.996
F10
Coagulation factor X.
  
0.973
TFPI
Tissue factor pathway inhibitor.
    
 0.969
F2
Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.
  
0.858
SERPINC1
Serpin family C member 1; Belongs to the serpin family.
   
 0.856
POFUT1
Protein O-fucosyltransferase 1.
    
   0.827
POGLUT1
Protein O-glucosyltransferase 1.
    
   0.827
F8
Coagulation factor VIII; Belongs to the multicopper oxidase family.
   
 0.789
F9
Coagulation factor IX.
  
 
0.786
GGCX
Gamma-glutamyl carboxylase.
    
 0.773
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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