node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BRCA2 | FANCA | ENSMNEP00000025034 | ENSMNEP00000002731 | BRCA2 DNA repair associated. | FA complementation group A. | 0.574 |
BRCA2 | FANCB | ENSMNEP00000025034 | ENSMNEP00000018561 | BRCA2 DNA repair associated. | FA complementation group B. | 0.526 |
BRCA2 | FANCC | ENSMNEP00000025034 | ENSMNEP00000009423 | BRCA2 DNA repair associated. | Fanconi anemia group C protein homolog; DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1. | 0.554 |
BRCA2 | FANCD2 | ENSMNEP00000025034 | ENSMNEP00000003465 | BRCA2 DNA repair associated. | Uncharacterized protein. | 0.990 |
BRCA2 | FANCE | ENSMNEP00000025034 | ENSMNEP00000029120 | BRCA2 DNA repair associated. | FA complementation group E. | 0.489 |
BRCA2 | FANCG | ENSMNEP00000025034 | ENSMNEP00000038617 | BRCA2 DNA repair associated. | FA complementation group G. | 0.787 |
BRCA2 | FANCI | ENSMNEP00000025034 | ENSMNEP00000042331 | BRCA2 DNA repair associated. | FA complementation group I. | 0.744 |
BRCA2 | FANCL | ENSMNEP00000025034 | ENSMNEP00000008692 | BRCA2 DNA repair associated. | FA complementation group L. | 0.554 |
BRCA2 | UBE2T | ENSMNEP00000025034 | ENSMNEP00000045740 | BRCA2 DNA repair associated. | Ubiquitin conjugating enzyme E2 T; Belongs to the ubiquitin-conjugating enzyme family. | 0.429 |
FAN1 | FANCA | ENSMNEP00000016438 | ENSMNEP00000002731 | Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. | FA complementation group A. | 0.672 |
FAN1 | FANCB | ENSMNEP00000016438 | ENSMNEP00000018561 | Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. | FA complementation group B. | 0.639 |
FAN1 | FANCC | ENSMNEP00000016438 | ENSMNEP00000009423 | Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. | Fanconi anemia group C protein homolog; DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1. | 0.529 |
FAN1 | FANCD2 | ENSMNEP00000016438 | ENSMNEP00000003465 | Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. | Uncharacterized protein. | 0.980 |
FAN1 | FANCE | ENSMNEP00000016438 | ENSMNEP00000029120 | Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. | FA complementation group E. | 0.407 |
FAN1 | FANCG | ENSMNEP00000016438 | ENSMNEP00000038617 | Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. | FA complementation group G. | 0.554 |
FAN1 | FANCI | ENSMNEP00000016438 | ENSMNEP00000042331 | Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. | FA complementation group I. | 0.798 |
FAN1 | FANCL | ENSMNEP00000016438 | ENSMNEP00000008692 | Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. | FA complementation group L. | 0.744 |
FAN1 | UBE2T | ENSMNEP00000016438 | ENSMNEP00000045740 | Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. | Ubiquitin conjugating enzyme E2 T; Belongs to the ubiquitin-conjugating enzyme family. | 0.506 |
FANCA | BRCA2 | ENSMNEP00000002731 | ENSMNEP00000025034 | FA complementation group A. | BRCA2 DNA repair associated. | 0.574 |
FANCA | FAN1 | ENSMNEP00000002731 | ENSMNEP00000016438 | FA complementation group A. | Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. | 0.672 |