STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SETD2SET domain containing 2, histone lysine methyltransferase. (2520 aa)    
Predicted Functional Partners:
ASH1L
ASH1 like histone lysine methyltransferase.
   
 
0.966
POLR2A
DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.941
H3-4
Histone H3; Belongs to the histone H3 family.
   
 0.927
POLR2C
RNA polymerase II subunit C.
    
 0.920
POLR2B
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.898
SETD1B
SET domain containing 1B, histone lysine methyltransferase.
   
0.881
SETD1A
Uncharacterized protein.
   
0.881
TRIP12
Thyroid hormone receptor interactor 12.
   
  
 0.835
KMT2E
Lysine methyltransferase 2E.
   
0.830
HNRNPL
Uncharacterized protein.
    
   0.829
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.