IER5L protein (Macaca nemestrina) - STRING interaction network

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Known Interactions

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Predicted Interactions

gene neighborhood

gene fusions

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textmining

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protein homology

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[Homology]

Score

IER5L

Immediate early response 5 like. (405 aa)

Predicted Functional Partners:

ANO8

0.695

TM9SF4

0.669

CELSR3

0.603

EPHA1

0.571

MED12

0.559

NAA25

0.497

SGTB

0.493

GET3

0.485

ANO3

0.418

LIN7A

0.400

Your Current Organism:

Macaca nemestrina

NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANO3	IER5L	ENSMNEP00000019816	ENSMNEP00000004788	Anoctamin.	Immediate early response 5 like.	0.418
ANO8	CELSR3	ENSMNEP00000011273	ENSMNEP00000044940	Anoctamin.	Cadherin EGF LAG seven-pass G-type receptor 3; Belongs to the G-protein coupled receptor 2 family.	0.504
ANO8	IER5L	ENSMNEP00000011273	ENSMNEP00000004788	Anoctamin.	Immediate early response 5 like.	0.695
ANO8	TM9SF4	ENSMNEP00000011273	ENSMNEP00000037433	Anoctamin.	Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.	0.562
CELSR3	ANO8	ENSMNEP00000044940	ENSMNEP00000011273	Cadherin EGF LAG seven-pass G-type receptor 3; Belongs to the G-protein coupled receptor 2 family.	Anoctamin.	0.504
CELSR3	IER5L	ENSMNEP00000044940	ENSMNEP00000004788	Cadherin EGF LAG seven-pass G-type receptor 3; Belongs to the G-protein coupled receptor 2 family.	Immediate early response 5 like.	0.603
EPHA1	IER5L	ENSMNEP00000037436	ENSMNEP00000004788	EPH receptor A1.	Immediate early response 5 like.	0.571
GET3	IER5L	ENSMNEP00000008105	ENSMNEP00000004788	ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]	Immediate early response 5 like.	0.485
GET3	NAA25	ENSMNEP00000008105	ENSMNEP00000003131	ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]	N(alpha)-acetyltransferase 25, NatB auxiliary subunit.	0.489
GET3	SGTB	ENSMNEP00000008105	ENSMNEP00000044219	ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]	Small glutamine rich tetratricopeptide repeat containing beta.	0.837
IER5L	ANO3	ENSMNEP00000004788	ENSMNEP00000019816	Immediate early response 5 like.	Anoctamin.	0.418
IER5L	ANO8	ENSMNEP00000004788	ENSMNEP00000011273	Immediate early response 5 like.	Anoctamin.	0.695
IER5L	CELSR3	ENSMNEP00000004788	ENSMNEP00000044940	Immediate early response 5 like.	Cadherin EGF LAG seven-pass G-type receptor 3; Belongs to the G-protein coupled receptor 2 family.	0.603
IER5L	EPHA1	ENSMNEP00000004788	ENSMNEP00000037436	Immediate early response 5 like.	EPH receptor A1.	0.571
IER5L	GET3	ENSMNEP00000004788	ENSMNEP00000008105	Immediate early response 5 like.	ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]	0.485
IER5L	LIN7A	ENSMNEP00000004788	ENSMNEP00000035211	Immediate early response 5 like.	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family.	0.400
IER5L	MED12	ENSMNEP00000004788	ENSMNEP00000037685	Immediate early response 5 like.	Mediator complex subunit 12.	0.559
IER5L	NAA25	ENSMNEP00000004788	ENSMNEP00000003131	Immediate early response 5 like.	N(alpha)-acetyltransferase 25, NatB auxiliary subunit.	0.497
IER5L	SGTB	ENSMNEP00000004788	ENSMNEP00000044219	Immediate early response 5 like.	Small glutamine rich tetratricopeptide repeat containing beta.	0.493
IER5L	TM9SF4	ENSMNEP00000004788	ENSMNEP00000037433	Immediate early response 5 like.	Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.	0.669