node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CCNT1 | CD4 | ENSMNEP00000039006 | ENSMNEP00000040289 | Cyclin T1; Belongs to the cyclin family. | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] | 0.678 |
CCNT1 | RAG2 | ENSMNEP00000039006 | ENSMNEP00000004854 | Cyclin T1; Belongs to the cyclin family. | Recombination activating 2. | 0.752 |
CD34 | CD4 | ENSMNEP00000035715 | ENSMNEP00000040289 | CD34 molecule. | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] | 0.896 |
CD34 | RAG1 | ENSMNEP00000035715 | ENSMNEP00000001690 | CD34 molecule. | V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] | 0.564 |
CD34 | RAG2 | ENSMNEP00000035715 | ENSMNEP00000004854 | CD34 molecule. | Recombination activating 2. | 0.725 |
CD4 | CCNT1 | ENSMNEP00000040289 | ENSMNEP00000039006 | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] | Cyclin T1; Belongs to the cyclin family. | 0.678 |
CD4 | CD34 | ENSMNEP00000040289 | ENSMNEP00000035715 | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] | CD34 molecule. | 0.896 |
CD4 | RAG1 | ENSMNEP00000040289 | ENSMNEP00000001690 | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] | V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] | 0.603 |
CD4 | RAG2 | ENSMNEP00000040289 | ENSMNEP00000004854 | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] | Recombination activating 2. | 0.677 |
CD4 | TMEM232 | ENSMNEP00000040289 | ENSMNEP00000017286 | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] | Transmembrane protein 232. | 0.469 |
ENSMNEP00000001525 | RAG2 | ENSMNEP00000001525 | ENSMNEP00000004854 | Uncharacterized protein. | Recombination activating 2. | 0.666 |
ENSMNEP00000015048 | H3-4 | ENSMNEP00000015048 | ENSMNEP00000004001 | Histone domain-containing protein. | Histone H3; Belongs to the histone H3 family. | 0.718 |
ENSMNEP00000015048 | RAG2 | ENSMNEP00000015048 | ENSMNEP00000004854 | Histone domain-containing protein. | Recombination activating 2. | 0.691 |
H3-4 | ENSMNEP00000015048 | ENSMNEP00000004001 | ENSMNEP00000015048 | Histone H3; Belongs to the histone H3 family. | Histone domain-containing protein. | 0.718 |
H3-4 | LOC105469173 | ENSMNEP00000004001 | ENSMNEP00000007555 | Histone H3; Belongs to the histone H3 family. | Histone H3; Belongs to the histone H3 family. | 0.717 |
H3-4 | LOC105476302 | ENSMNEP00000004001 | ENSMNEP00000010223 | Histone H3; Belongs to the histone H3 family. | Histone H3.3. | 0.717 |
H3-4 | RAG2 | ENSMNEP00000004001 | ENSMNEP00000004854 | Histone H3; Belongs to the histone H3 family. | Recombination activating 2. | 0.689 |
LOC105469173 | H3-4 | ENSMNEP00000007555 | ENSMNEP00000004001 | Histone H3; Belongs to the histone H3 family. | Histone H3; Belongs to the histone H3 family. | 0.717 |
LOC105469173 | RAG2 | ENSMNEP00000007555 | ENSMNEP00000004854 | Histone H3; Belongs to the histone H3 family. | Recombination activating 2. | 0.691 |
LOC105476302 | H3-4 | ENSMNEP00000010223 | ENSMNEP00000004001 | Histone H3.3. | Histone H3; Belongs to the histone H3 family. | 0.717 |