STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RHBDL3Rhomboid-related protein 3; May be involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors; Belongs to the peptidase S54 family. (404 aa)    
Predicted Functional Partners:
CASK
Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family.
   
 0.829
WDR90
WD repeat domain 90.
   
 
 0.730
MAGI3
Membrane associated guanylate kinase, WW and PDZ domain containing 3.
  
 0.676
LRGUK
Leucine rich repeats and guanylate kinase domain containing.
  
 0.660
MYO3A
Myosin IIIA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
   
 0.564
MYO3B
Myosin IIIB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
   
 0.564
VPS18
VPS18 core subunit of CORVET and HOPS complexes.
      
 0.489
MYO9A
Myosin IXA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
    
 0.480
MYO9B
Myosin IXB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
    
 0.480
MTHFSD
Methenyltetrahydrofolate synthetase domain containing.
  
   0.463
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.