NLRP10 protein (Macaca nemestrina) - STRING interaction network

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Score

NLRP10

NLR family pyrin domain containing 10. (663 aa)

Predicted Functional Partners:

PYCARD

0.669

NAIP

0.630

RIPK2

0.501

TXNIP

0.438

IL1B

0.429

ENSMNEP00000007520

0.401

Your Current Organism:

Macaca nemestrina

NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSMNEP00000007520	IL1B	ENSMNEP00000007520	ENSMNEP00000033521	CARD domain-containing protein.	Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family.	0.558
ENSMNEP00000007520	NAIP	ENSMNEP00000007520	ENSMNEP00000012364	CARD domain-containing protein.	NLR family apoptosis inhibitory protein.	0.996
ENSMNEP00000007520	NLRP10	ENSMNEP00000007520	ENSMNEP00000005715	CARD domain-containing protein.	NLR family pyrin domain containing 10.	0.401
ENSMNEP00000007520	PYCARD	ENSMNEP00000007520	ENSMNEP00000036486	CARD domain-containing protein.	PYD and CARD domain containing.	0.966
IL1B	ENSMNEP00000007520	ENSMNEP00000033521	ENSMNEP00000007520	Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family.	CARD domain-containing protein.	0.558
IL1B	NLRP10	ENSMNEP00000033521	ENSMNEP00000005715	Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family.	NLR family pyrin domain containing 10.	0.429
IL1B	PYCARD	ENSMNEP00000033521	ENSMNEP00000036486	Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family.	PYD and CARD domain containing.	0.964
IL1B	TXNIP	ENSMNEP00000033521	ENSMNEP00000039922	Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family.	Thioredoxin interacting protein.	0.493
NAIP	ENSMNEP00000007520	ENSMNEP00000012364	ENSMNEP00000007520	NLR family apoptosis inhibitory protein.	CARD domain-containing protein.	0.996
NAIP	NLRP10	ENSMNEP00000012364	ENSMNEP00000005715	NLR family apoptosis inhibitory protein.	NLR family pyrin domain containing 10.	0.630
NAIP	PYCARD	ENSMNEP00000012364	ENSMNEP00000036486	NLR family apoptosis inhibitory protein.	PYD and CARD domain containing.	0.503
NAIP	RIPK2	ENSMNEP00000012364	ENSMNEP00000038120	NLR family apoptosis inhibitory protein.	Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains.	0.739
NLRP10	ENSMNEP00000007520	ENSMNEP00000005715	ENSMNEP00000007520	NLR family pyrin domain containing 10.	CARD domain-containing protein.	0.401
NLRP10	IL1B	ENSMNEP00000005715	ENSMNEP00000033521	NLR family pyrin domain containing 10.	Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family.	0.429
NLRP10	NAIP	ENSMNEP00000005715	ENSMNEP00000012364	NLR family pyrin domain containing 10.	NLR family apoptosis inhibitory protein.	0.630
NLRP10	PYCARD	ENSMNEP00000005715	ENSMNEP00000036486	NLR family pyrin domain containing 10.	PYD and CARD domain containing.	0.669
NLRP10	RIPK2	ENSMNEP00000005715	ENSMNEP00000038120	NLR family pyrin domain containing 10.	Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains.	0.501
NLRP10	TXNIP	ENSMNEP00000005715	ENSMNEP00000039922	NLR family pyrin domain containing 10.	Thioredoxin interacting protein.	0.438
PYCARD	ENSMNEP00000007520	ENSMNEP00000036486	ENSMNEP00000007520	PYD and CARD domain containing.	CARD domain-containing protein.	0.966
PYCARD	IL1B	ENSMNEP00000036486	ENSMNEP00000033521	PYD and CARD domain containing.	Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family.	0.964