STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIGLEC11Sialic acid binding Ig like lectin 11. (553 aa)    
Predicted Functional Partners:
IL4
Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family.
  
   
 0.478
TYROBP
TYRO protein tyrosine kinase binding protein.
   
 0.442
CSF2RB
Colony stimulating factor 2 receptor beta common subunit.
  
   0.436
ENSMNEP00000040460
Uncharacterized protein.
  
  
 0.426
CDH24
Cadherin 24; Cadherins are calcium-dependent cell adhesion proteins.
    
 
 0.423
FCRL1
Fc receptor like 1.
  
 
 0.419
CD22
CD22 molecule.
   
 
0.418
BPIFA1
BPI fold containing family A member 1.
  
     0.413
OMG
Oligodendrocyte myelin glycoprotein.
   
 0.410
SSMEM1
Serine rich single-pass membrane protein 1.
  
     0.402
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.