STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KCNH3Potassium voltage-gated channel subfamily H member 3. (1083 aa)    
Predicted Functional Partners:
SLITRK1
SLIT and NTRK like family member 1.
     
 0.837
KCNF1
Potassium voltage-gated channel modifier subfamily F member 1; Belongs to the potassium channel family.
     
 0.834
OPCML
Opioid binding protein/cell adhesion molecule like.
      
 0.833
KCNAB3
Potassium voltage-gated channel subfamily A regulatory beta subunit 3.
     
 0.825
CACNB1
Calcium voltage-gated channel auxiliary subunit beta 1.
      
 0.813
SCN1A
Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
   
 
 0.714
NTRK2
Tyrosine-protein kinase receptor.
    
 
 0.698
SYN2
Synapsin II.
   
  
 0.678
KCNK4
Potassium two pore domain channel subfamily K member 4; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
   
 
 0.678
GABRA5
Gamma-aminobutyric acid type A receptor alpha5 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
      
 0.674
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.