STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDARADDEDAR associated death domain. (215 aa)    
Predicted Functional Partners:
EDAR
Ectodysplasin A receptor.
    
 0.959
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.940
PUM1
Pumilio RNA binding family member 1.
   
 
 0.715
PUM2
Pumilio RNA binding family member 2.
   
 
 0.715
CNOT1
CCR4-NOT transcription complex subunit 1.
    
 
 0.692
ENSMNEP00000012002
TNF receptor-associated factor.
    
 0.662
EDA
Ectodysplasin A; Belongs to the tumor necrosis factor family.
     
 0.514
ENSMNEP00000005495
T-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.
      
 0.470
CCT7
T-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.
      
 0.470
WNT10A
Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.
   
  
 0.409
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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