STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAP2BRAP2B, member of RAS oncogene family. (183 aa)    
Predicted Functional Partners:
ITSN2
Intersectin 2.
    
 0.914
ITSN1
Intersectin 1.
    
 0.829
NOS1AP
PID domain-containing protein.
    
 0.763
RAPGEF4
Rap guanine nucleotide exchange factor 4.
    
 0.723
RAPGEF2
Rap guanine nucleotide exchange factor 2.
   
 0.673
SHANK3
SH3 and multiple ankyrin repeat domains 3.
    
 0.667
SHANK1
SH3 and multiple ankyrin repeat domains 1.
    
 0.667
NF1
Neurofibromin 1.
    
 0.648
MST1R
Macrophage stimulating 1 receptor.
   
 0.617
MET
MET proto-oncogene, receptor tyrosine kinase.
   
 0.617
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.