STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SGTASmall glutamine rich tetratricopeptide repeat containing alpha. (313 aa)    
Predicted Functional Partners:
GET4
Guided entry of tail-anchored proteins factor 4.
   
 0.929
BAG6
BCL2 associated athanogene 6.
   
 0.916
LEO1
LEO1 homolog, Paf1/RNA polymerase II complex component.
    
 0.872
GET3
ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]
   
 0.839
UBL4A
Ubiquitin like 4A.
   
 0.813
HSPH1
Heat shock protein family H (Hsp110) member 1.
   
 0.750
HSPA4
Heat shock protein family A (Hsp70) member 4.
   
 0.731
SEC61B
Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.
   
 0.731
RAD23A
RAD23 homolog A, nucleotide excision repair protein.
   
 0.727
RAD23B
RAD23 homolog B, nucleotide excision repair protein.
   
 0.716
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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