node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BAG6 | GET3 | ENSMNEP00000025790 | ENSMNEP00000008105 | BCL2 associated athanogene 6. | ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...] | 0.818 |
BAG6 | GET4 | ENSMNEP00000025790 | ENSMNEP00000044524 | BCL2 associated athanogene 6. | Guided entry of tail-anchored proteins factor 4. | 0.981 |
BAG6 | SGTA | ENSMNEP00000025790 | ENSMNEP00000006883 | BCL2 associated athanogene 6. | Small glutamine rich tetratricopeptide repeat containing alpha. | 0.916 |
BAG6 | UBL4A | ENSMNEP00000025790 | ENSMNEP00000032364 | BCL2 associated athanogene 6. | Ubiquitin like 4A. | 0.970 |
GET3 | BAG6 | ENSMNEP00000008105 | ENSMNEP00000025790 | ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...] | BCL2 associated athanogene 6. | 0.818 |
GET3 | GET4 | ENSMNEP00000008105 | ENSMNEP00000044524 | ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...] | Guided entry of tail-anchored proteins factor 4. | 0.978 |
GET3 | RAD23A | ENSMNEP00000008105 | ENSMNEP00000038317 | ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...] | RAD23 homolog A, nucleotide excision repair protein. | 0.924 |
GET3 | RAD23B | ENSMNEP00000008105 | ENSMNEP00000032160 | ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...] | RAD23 homolog B, nucleotide excision repair protein. | 0.923 |
GET3 | SEC61B | ENSMNEP00000008105 | ENSMNEP00000041625 | ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...] | Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum. | 0.796 |
GET3 | SGTA | ENSMNEP00000008105 | ENSMNEP00000006883 | ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...] | Small glutamine rich tetratricopeptide repeat containing alpha. | 0.839 |
GET3 | UBL4A | ENSMNEP00000008105 | ENSMNEP00000032364 | ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...] | Ubiquitin like 4A. | 0.692 |
GET4 | BAG6 | ENSMNEP00000044524 | ENSMNEP00000025790 | Guided entry of tail-anchored proteins factor 4. | BCL2 associated athanogene 6. | 0.981 |
GET4 | GET3 | ENSMNEP00000044524 | ENSMNEP00000008105 | Guided entry of tail-anchored proteins factor 4. | ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...] | 0.978 |
GET4 | RAD23A | ENSMNEP00000044524 | ENSMNEP00000038317 | Guided entry of tail-anchored proteins factor 4. | RAD23 homolog A, nucleotide excision repair protein. | 0.872 |
GET4 | RAD23B | ENSMNEP00000044524 | ENSMNEP00000032160 | Guided entry of tail-anchored proteins factor 4. | RAD23 homolog B, nucleotide excision repair protein. | 0.872 |
GET4 | SEC61B | ENSMNEP00000044524 | ENSMNEP00000041625 | Guided entry of tail-anchored proteins factor 4. | Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum. | 0.562 |
GET4 | SGTA | ENSMNEP00000044524 | ENSMNEP00000006883 | Guided entry of tail-anchored proteins factor 4. | Small glutamine rich tetratricopeptide repeat containing alpha. | 0.929 |
GET4 | UBL4A | ENSMNEP00000044524 | ENSMNEP00000032364 | Guided entry of tail-anchored proteins factor 4. | Ubiquitin like 4A. | 0.932 |
HSPA4 | HSPH1 | ENSMNEP00000011997 | ENSMNEP00000017049 | Heat shock protein family A (Hsp70) member 4. | Heat shock protein family H (Hsp110) member 1. | 0.668 |
HSPA4 | SGTA | ENSMNEP00000011997 | ENSMNEP00000006883 | Heat shock protein family A (Hsp70) member 4. | Small glutamine rich tetratricopeptide repeat containing alpha. | 0.731 |