STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (706 aa)    
Predicted Functional Partners:
CARD11
Caspase recruitment domain family member 11.
   
 0.979
IKBKB
Inhibitor of nuclear factor kappa B kinase subunit beta.
  
 
0.968
CD28
CD28 molecule.
    
 0.958
CHUK
Component of inhibitor of nuclear factor kappa B kinase complex.
  
 
0.951
PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.
    
 0.946
RELA
RELA proto-oncogene, NF-kB subunit.
   
 0.938
IKBKG
Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.
   
 0.937
PTPN6
Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.
   
 0.933
NFKB1
Nuclear factor kappa B subunit 1.
   
 0.930
CARD10
Caspase recruitment domain family member 10.
    
 0.929
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.