STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DEGS2Delta 4-desaturase, sphingolipid 2. (323 aa)    
Predicted Functional Partners:
PLPP2
Phospholipid phosphatase 2.
     
 0.995
CERS4
Ceramide synthase 4.
   
 0.968
UGCG
UDP-glucose ceramide glucosyltransferase.
   
 
 0.954
KDSR
3-ketodihydrosphingosine reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 
 0.948
SMPD2
Sphingomyelin phosphodiesterase 2.
     
 0.945
SGMS2
Sphingomyelin synthase 2.
   
 
 0.939
SGMS1
Sphingomyelin synthase 1.
   
 
 0.939
SPHK1
Sphingosine kinase 1.
    
 0.938
ASAH2
Neutral ceramidase.
     
 0.938
SPHK2
Sphingosine kinase 2.
    
 0.938
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.