HOXD8 protein (Macaca nemestrina) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

Experiments

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[Homology]

Score

HOXD8

Homeobox D8. (265 aa)

Predicted Functional Partners:

COL2A1

0.700

PBX1

0.650

PBX2

0.650

PBX3

0.650

PBX4

0.650

MEIS2

0.626

MKX

0.623

CUX2

0.594

LIM2

0.576

HOXC9

0.545

Your Current Organism:

Macaca nemestrina

NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
COL2A1	HOXD8	ENSMNEP00000020889	ENSMNEP00000007128	Collagen type II alpha 1 chain.	Homeobox D8.	0.700
CUX2	HOXC9	ENSMNEP00000032698	ENSMNEP00000026097	Cut like homeobox 2.	Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family.	0.586
CUX2	HOXD8	ENSMNEP00000032698	ENSMNEP00000007128	Cut like homeobox 2.	Homeobox D8.	0.594
CUX2	LIM2	ENSMNEP00000032698	ENSMNEP00000040880	Cut like homeobox 2.	Lens fiber membrane intrinsic protein; Present in the thicker 16-17 nm junctions of mammalian lens fiber cells, where it may contribute to cell junctional organization. Acts as a receptor for calmodulin. May play an important role in both lens development and cataractogenesis; Belongs to the PMP-22/EMP/MP20 family.	0.579
CUX2	MEIS2	ENSMNEP00000032698	ENSMNEP00000009857	Cut like homeobox 2.	Meis homeobox 2.	0.473
CUX2	MKX	ENSMNEP00000032698	ENSMNEP00000032977	Cut like homeobox 2.	Mohawk homeobox.	0.586
HOXC9	CUX2	ENSMNEP00000026097	ENSMNEP00000032698	Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family.	Cut like homeobox 2.	0.586
HOXC9	HOXD8	ENSMNEP00000026097	ENSMNEP00000007128	Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family.	Homeobox D8.	0.545
HOXC9	LIM2	ENSMNEP00000026097	ENSMNEP00000040880	Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family.	Lens fiber membrane intrinsic protein; Present in the thicker 16-17 nm junctions of mammalian lens fiber cells, where it may contribute to cell junctional organization. Acts as a receptor for calmodulin. May play an important role in both lens development and cataractogenesis; Belongs to the PMP-22/EMP/MP20 family.	0.576
HOXC9	MEIS2	ENSMNEP00000026097	ENSMNEP00000009857	Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family.	Meis homeobox 2.	0.523
HOXC9	MKX	ENSMNEP00000026097	ENSMNEP00000032977	Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family.	Mohawk homeobox.	0.623
HOXC9	PBX1	ENSMNEP00000026097	ENSMNEP00000025887	Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family.	PBX homeobox 1.	0.827
HOXC9	PBX2	ENSMNEP00000026097	ENSMNEP00000026802	Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family.	PBX homeobox 2.	0.827
HOXC9	PBX3	ENSMNEP00000026097	ENSMNEP00000029077	Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family.	PBX homeobox 3.	0.827
HOXC9	PBX4	ENSMNEP00000026097	ENSMNEP00000037041	Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family.	PBX homeobox 4.	0.827
HOXD8	COL2A1	ENSMNEP00000007128	ENSMNEP00000020889	Homeobox D8.	Collagen type II alpha 1 chain.	0.700
HOXD8	CUX2	ENSMNEP00000007128	ENSMNEP00000032698	Homeobox D8.	Cut like homeobox 2.	0.594
HOXD8	HOXC9	ENSMNEP00000007128	ENSMNEP00000026097	Homeobox D8.	Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family.	0.545
HOXD8	LIM2	ENSMNEP00000007128	ENSMNEP00000040880	Homeobox D8.	Lens fiber membrane intrinsic protein; Present in the thicker 16-17 nm junctions of mammalian lens fiber cells, where it may contribute to cell junctional organization. Acts as a receptor for calmodulin. May play an important role in both lens development and cataractogenesis; Belongs to the PMP-22/EMP/MP20 family.	0.576
HOXD8	MEIS2	ENSMNEP00000007128	ENSMNEP00000009857	Homeobox D8.	Meis homeobox 2.	0.626