NFE2L2 protein (Macaca nemestrina) - STRING interaction network

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Score

NFE2L2

Nuclear factor, erythroid 2 like 2. (618 aa)

Predicted Functional Partners:

KEAP1

0.998

MAFG

0.959

KLHL17

0.952

EIF2AK3

0.943

DDIT3

0.936

EIF2AK2

0.933

MAPK7

0.932

EIF2AK1

0.917

MAFK

0.910

KLHL18

0.909

Your Current Organism:

Macaca nemestrina

NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DDIT3	EIF2AK2	ENSMNEP00000000014	ENSMNEP00000033718	DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...]	Eukaryotic translation initiation factor 2 alpha kinase 2.	0.423
DDIT3	EIF2AK3	ENSMNEP00000000014	ENSMNEP00000018152	DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...]	Eukaryotic translation initiation factor 2 alpha kinase 3.	0.477
DDIT3	NFE2L2	ENSMNEP00000000014	ENSMNEP00000007318	DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...]	Nuclear factor, erythroid 2 like 2.	0.936
EIF2AK1	EIF2AK2	ENSMNEP00000018383	ENSMNEP00000033718	Eukaryotic translation initiation factor 2 alpha kinase 1.	Eukaryotic translation initiation factor 2 alpha kinase 2.	0.899
EIF2AK1	EIF2AK3	ENSMNEP00000018383	ENSMNEP00000018152	Eukaryotic translation initiation factor 2 alpha kinase 1.	Eukaryotic translation initiation factor 2 alpha kinase 3.	0.891
EIF2AK1	NFE2L2	ENSMNEP00000018383	ENSMNEP00000007318	Eukaryotic translation initiation factor 2 alpha kinase 1.	Nuclear factor, erythroid 2 like 2.	0.917
EIF2AK2	DDIT3	ENSMNEP00000033718	ENSMNEP00000000014	Eukaryotic translation initiation factor 2 alpha kinase 2.	DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...]	0.423
EIF2AK2	EIF2AK1	ENSMNEP00000033718	ENSMNEP00000018383	Eukaryotic translation initiation factor 2 alpha kinase 2.	Eukaryotic translation initiation factor 2 alpha kinase 1.	0.899
EIF2AK2	EIF2AK3	ENSMNEP00000033718	ENSMNEP00000018152	Eukaryotic translation initiation factor 2 alpha kinase 2.	Eukaryotic translation initiation factor 2 alpha kinase 3.	0.869
EIF2AK2	NFE2L2	ENSMNEP00000033718	ENSMNEP00000007318	Eukaryotic translation initiation factor 2 alpha kinase 2.	Nuclear factor, erythroid 2 like 2.	0.933
EIF2AK3	DDIT3	ENSMNEP00000018152	ENSMNEP00000000014	Eukaryotic translation initiation factor 2 alpha kinase 3.	DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...]	0.477
EIF2AK3	EIF2AK1	ENSMNEP00000018152	ENSMNEP00000018383	Eukaryotic translation initiation factor 2 alpha kinase 3.	Eukaryotic translation initiation factor 2 alpha kinase 1.	0.891
EIF2AK3	EIF2AK2	ENSMNEP00000018152	ENSMNEP00000033718	Eukaryotic translation initiation factor 2 alpha kinase 3.	Eukaryotic translation initiation factor 2 alpha kinase 2.	0.869
EIF2AK3	NFE2L2	ENSMNEP00000018152	ENSMNEP00000007318	Eukaryotic translation initiation factor 2 alpha kinase 3.	Nuclear factor, erythroid 2 like 2.	0.943
KEAP1	NFE2L2	ENSMNEP00000036269	ENSMNEP00000007318	Kelch like ECH associated protein 1.	Nuclear factor, erythroid 2 like 2.	0.998
KLHL17	NFE2L2	ENSMNEP00000022917	ENSMNEP00000007318	Kelch like family member 17.	Nuclear factor, erythroid 2 like 2.	0.952
KLHL18	NFE2L2	ENSMNEP00000019608	ENSMNEP00000007318	Kelch like family member 18.	Nuclear factor, erythroid 2 like 2.	0.909
MAFG	MAFK	ENSMNEP00000003943	ENSMNEP00000020524	MAF bZIP transcription factor G.	MAF bZIP transcription factor K.	0.673
MAFG	NFE2L2	ENSMNEP00000003943	ENSMNEP00000007318	MAF bZIP transcription factor G.	Nuclear factor, erythroid 2 like 2.	0.959
MAFK	MAFG	ENSMNEP00000020524	ENSMNEP00000003943	MAF bZIP transcription factor K.	MAF bZIP transcription factor G.	0.673