STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BATFBasic leucine zipper ATF-like transcription factor. (125 aa)    
Predicted Functional Partners:
JUNB
JunB proto-oncogene, AP-1 transcription factor subunit.
   
 0.950
BATF2
Basic leucine zipper ATF-like transcription factor 2.
   
 
0.922
BATF3
Basic leucine zipper ATF-like transcription factor 3.
   
 
0.900
IRF4
Interferon regulatory factor 4.
   
 
 0.775
SPC25
SPC25 component of NDC80 kinetochore complex.
    
 0.684
NUF2
NUF2 component of NDC80 kinetochore complex.
   
 0.674
NDC80
NDC80 kinetochore complex component.
    
 0.608
ICOS
Inducible T cell costimulator.
   
  
 0.593
BCL6
BCL6 transcription repressor.
    
 0.587
CD4
T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]
   
  
 0.586
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.