Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TRIB1Tribbles pseudokinase 1. (372 aa)    
Predicted Functional Partners:
COP1
COP1 E3 ubiquitin ligase.
    
 
 0.925
STK40
Serine/threonine kinase 40.
    
   0.903
FOSL2
FOS like 2, AP-1 transcription factor subunit.
   
 0.899
TRIB2
Tribbles pseudokinase 2.
    
   0.896
UBE2E1
Ubiquitin conjugating enzyme E2 E1; Belongs to the ubiquitin-conjugating enzyme family.
    
   0.893
DET1
Uncharacterized protein.
    
 
 0.828
CEBPE
CCAAT/enhancer-binding protein.
    
 0.823
RIBC2
RIB43A domain with coiled-coils 2.
   
 0.740
ATF4
Activating transcription factor 4.
   
 0.731
AKT1
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 0.701
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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