ENSMNEP00000009950 protein (Macaca nemestrina)

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Score

ENSMNEP00000009950

Uncharacterized protein; Belongs to the cytochrome P450 family. (129 aa)

Predicted Functional Partners:

HSD11B2

0.902

SRD5A3

0.891

HSD3B2

0.889

ENSMNEP00000044019

0.889

CYP11A1

0.887

HSD3B1

0.879

HSD11B1

0.878

ENSMNEP00000006490

0.877

SRD5A2

0.874

SRD5A1

0.874

Your Current Organism:

Macaca nemestrina

NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CYP11A1	ENSMNEP00000009950	ENSMNEP00000041281	ENSMNEP00000009950	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.887
CYP11A1	ENSMNEP00000044019	ENSMNEP00000041281	ENSMNEP00000044019	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	3Beta_HSD domain-containing protein; Belongs to the 3-beta-HSD family.	0.941
CYP11A1	HSD11B1	ENSMNEP00000041281	ENSMNEP00000031303	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	Hydroxysteroid 11-beta dehydrogenase 1.	0.567
CYP11A1	HSD11B2	ENSMNEP00000041281	ENSMNEP00000017407	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	Hydroxysteroid 11-beta dehydrogenase 2.	0.680
CYP11A1	HSD3B1	ENSMNEP00000041281	ENSMNEP00000031119	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1; Belongs to the 3-beta-HSD family.	0.966
CYP11A1	HSD3B2	ENSMNEP00000041281	ENSMNEP00000000936	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2; Belongs to the 3-beta-HSD family.	0.941
CYP11A1	SRD5A1	ENSMNEP00000041281	ENSMNEP00000035276	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	3-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology.	0.632
CYP11A1	SRD5A2	ENSMNEP00000041281	ENSMNEP00000003541	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	3-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology.	0.553
CYP11A1	SRD5A3	ENSMNEP00000041281	ENSMNEP00000015093	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	Steroid 5 alpha-reductase 3.	0.553
ENSMNEP00000006490	ENSMNEP00000009950	ENSMNEP00000006490	ENSMNEP00000009950	Uncharacterized protein.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.877
ENSMNEP00000006490	ENSMNEP00000044019	ENSMNEP00000006490	ENSMNEP00000044019	Uncharacterized protein.	3Beta_HSD domain-containing protein; Belongs to the 3-beta-HSD family.	0.890
ENSMNEP00000006490	HSD11B1	ENSMNEP00000006490	ENSMNEP00000031303	Uncharacterized protein.	Hydroxysteroid 11-beta dehydrogenase 1.	0.907
ENSMNEP00000006490	HSD11B2	ENSMNEP00000006490	ENSMNEP00000017407	Uncharacterized protein.	Hydroxysteroid 11-beta dehydrogenase 2.	0.925
ENSMNEP00000006490	HSD3B1	ENSMNEP00000006490	ENSMNEP00000031119	Uncharacterized protein.	Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1; Belongs to the 3-beta-HSD family.	0.916
ENSMNEP00000006490	HSD3B2	ENSMNEP00000006490	ENSMNEP00000000936	Uncharacterized protein.	Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2; Belongs to the 3-beta-HSD family.	0.890
ENSMNEP00000006490	SRD5A1	ENSMNEP00000006490	ENSMNEP00000035276	Uncharacterized protein.	3-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology.	0.947
ENSMNEP00000006490	SRD5A2	ENSMNEP00000006490	ENSMNEP00000003541	Uncharacterized protein.	3-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology.	0.947
ENSMNEP00000006490	SRD5A3	ENSMNEP00000006490	ENSMNEP00000015093	Uncharacterized protein.	Steroid 5 alpha-reductase 3.	0.891
ENSMNEP00000009950	CYP11A1	ENSMNEP00000009950	ENSMNEP00000041281	Uncharacterized protein; Belongs to the cytochrome P450 family.	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	0.887
ENSMNEP00000009950	ENSMNEP00000006490	ENSMNEP00000009950	ENSMNEP00000006490	Uncharacterized protein; Belongs to the cytochrome P450 family.	Uncharacterized protein.	0.877