STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMPD4Sphingomyelin phosphodiesterase 4. (835 aa)    
Predicted Functional Partners:
SMPD3
Sphingomyelin phosphodiesterase 3.
     
 0.936
SMPD2
Sphingomyelin phosphodiesterase 2.
     
 0.932
SGMS1
Sphingomyelin synthase 1.
     
 0.926
SMPD1
Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide.
     
 0.918
DEGS1
Delta 4-desaturase, sphingolipid 1.
     
 0.914
SGMS2
Sphingomyelin synthase 2.
     
 0.911
DEGS2
Delta 4-desaturase, sphingolipid 2.
     
 0.904
ASAH2
Neutral ceramidase.
     
 0.902
UGT8
UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.
     
 0.902
SGPP2
Sphingosine-1-phosphate phosphatase 2.
   
 
 0.901
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.