STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPIRE2Spire type actin nucleation factor 2. (714 aa)    
Predicted Functional Partners:
GRAP2
GRB2 related adaptor protein 2.
   
 0.880
MYO5A
Myosin VA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
   
 0.876
FMN2
Formin 2.
    
 0.851
FMN1
Formin 1.
    
 0.820
GRB2
Growth factor receptor bound protein 2.
   
 0.818
MYO5C
Myosin VC; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
   
 0.683
MYO5B
Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
   
 0.660
NCK1
Cytoplasmic protein.
    
 0.658
NCK2
Cytoplasmic protein.
    
 0.658
LAT
Linker for activation of T cells.
    
 0.638
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.