STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DOK1Docking protein 1. (454 aa)    
Predicted Functional Partners:
RET
Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands.
    
  0.934
RASA1
RAS p21 protein activator 1.
    
 
 0.919
ABL1
Tyrosine-protein kinase.
    
 0.728
PTK6
Tyrosine-protein kinase.
    
 0.680
CSK
Tyrosine-protein kinase.
    
 0.675
CRKL
CRK like proto-oncogene, adaptor protein.
    
 0.674
FYN
Tyrosine-protein kinase.
    
 0.663
ABL2
Tyrosine-protein kinase.
    
 0.630
INPP5D
Inositol polyphosphate-5-phosphatase D.
   
 
 0.619
CRK
CRK proto-oncogene, adaptor protein.
    
 0.615
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.