STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DOK4Docking protein 4. (365 aa)    
Predicted Functional Partners:
RET
Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands.
    
 0.624
PTPN6
Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.
    
 0.613
EFR3A
EFR3 homolog A.
      
 0.569
MAP2K4
Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily.
      
 0.555
GDNF
Glial cell derived neurotrophic factor.
     
 0.551
CRK
CRK proto-oncogene, adaptor protein.
    
 0.525
COL5A2
Collagen type V alpha 2 chain.
      
 0.521
SEMA3E
Semaphorin 3E; Belongs to the semaphorin family.
      
 0.512
CRKL
CRK like proto-oncogene, adaptor protein.
    
 0.488
PSPN
Persephin.
     
 0.477
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.