TOPORS protein (Macaca nemestrina) - STRING interaction network

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Score

TOPORS

TOP1 binding arginine/serine rich protein. (1047 aa)

Predicted Functional Partners:

UBE2I

0.697

USP45

0.616

KCTD2

0.613

SENP7

0.581

UBXN7

0.575

TOP1

0.561

KLHL7

0.560

SLC7A14

0.559

TBL2

0.555

PHACTR2

0.520

Your Current Organism:

Macaca nemestrina

NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KCTD2	SENP7	ENSMNEP00000041979	ENSMNEP00000021424	Potassium channel tetramerization domain containing 2.	SUMO specific peptidase 7.	0.415
KCTD2	TOP1	ENSMNEP00000041979	ENSMNEP00000031439	Potassium channel tetramerization domain containing 2.	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...]	0.699
KCTD2	TOPORS	ENSMNEP00000041979	ENSMNEP00000017991	Potassium channel tetramerization domain containing 2.	TOP1 binding arginine/serine rich protein.	0.613
KCTD2	UBXN7	ENSMNEP00000041979	ENSMNEP00000012940	Potassium channel tetramerization domain containing 2.	UBX domain-containing protein 7.	0.461
KLHL7	TOPORS	ENSMNEP00000025960	ENSMNEP00000017991	Kelch like family member 7.	TOP1 binding arginine/serine rich protein.	0.560
KLHL7	UBXN7	ENSMNEP00000025960	ENSMNEP00000012940	Kelch like family member 7.	UBX domain-containing protein 7.	0.440
KLHL7	USP45	ENSMNEP00000025960	ENSMNEP00000002730	Kelch like family member 7.	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.	0.636
PHACTR2	TBL2	ENSMNEP00000035529	ENSMNEP00000007341	Phosphatase and actin regulator.	Transducin beta like 2.	0.687
PHACTR2	TOPORS	ENSMNEP00000035529	ENSMNEP00000017991	Phosphatase and actin regulator.	TOP1 binding arginine/serine rich protein.	0.520
SENP7	KCTD2	ENSMNEP00000021424	ENSMNEP00000041979	SUMO specific peptidase 7.	Potassium channel tetramerization domain containing 2.	0.415
SENP7	TOPORS	ENSMNEP00000021424	ENSMNEP00000017991	SUMO specific peptidase 7.	TOP1 binding arginine/serine rich protein.	0.581
SENP7	UBE2I	ENSMNEP00000021424	ENSMNEP00000037152	SUMO specific peptidase 7.	Ubiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family.	0.449
SLC7A14	TOPORS	ENSMNEP00000043003	ENSMNEP00000017991	Solute carrier family 7 member 14.	TOP1 binding arginine/serine rich protein.	0.559
TBL2	PHACTR2	ENSMNEP00000007341	ENSMNEP00000035529	Transducin beta like 2.	Phosphatase and actin regulator.	0.687
TBL2	TOPORS	ENSMNEP00000007341	ENSMNEP00000017991	Transducin beta like 2.	TOP1 binding arginine/serine rich protein.	0.555
TOP1	KCTD2	ENSMNEP00000031439	ENSMNEP00000041979	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...]	Potassium channel tetramerization domain containing 2.	0.699
TOP1	TOPORS	ENSMNEP00000031439	ENSMNEP00000017991	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...]	TOP1 binding arginine/serine rich protein.	0.561
TOP1	UBE2I	ENSMNEP00000031439	ENSMNEP00000037152	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...]	Ubiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family.	0.699
TOPORS	KCTD2	ENSMNEP00000017991	ENSMNEP00000041979	TOP1 binding arginine/serine rich protein.	Potassium channel tetramerization domain containing 2.	0.613
TOPORS	KLHL7	ENSMNEP00000017991	ENSMNEP00000025960	TOP1 binding arginine/serine rich protein.	Kelch like family member 7.	0.560