node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CFL1 | TMSB10 | ENSMNEP00000019840 | ENSMNEP00000018336 | ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. | Thymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family. | 0.558 |
CLASP1 | TMSB10 | ENSMNEP00000043480 | ENSMNEP00000018336 | Cytoplasmic linker associated protein 1. | Thymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family. | 0.554 |
GPNMB | TMSB10 | ENSMNEP00000026716 | ENSMNEP00000018336 | Glycoprotein nmb. | Thymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family. | 0.455 |
IRX6 | KIF21A | ENSMNEP00000041830 | ENSMNEP00000045256 | Iroquois homeobox 6. | Kinesin family member 21A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. | 0.662 |
IRX6 | TMSB10 | ENSMNEP00000041830 | ENSMNEP00000018336 | Iroquois homeobox 6. | Thymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family. | 0.556 |
ITPA | PPP6C | ENSMNEP00000016008 | ENSMNEP00000024092 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. | Serine/threonine-protein phosphatase. | 0.520 |
ITPA | TMSB10 | ENSMNEP00000016008 | ENSMNEP00000018336 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. | Thymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family. | 0.520 |
KIF21A | IRX6 | ENSMNEP00000045256 | ENSMNEP00000041830 | Kinesin family member 21A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. | Iroquois homeobox 6. | 0.662 |
KIF21A | TMSB10 | ENSMNEP00000045256 | ENSMNEP00000018336 | Kinesin family member 21A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. | Thymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family. | 0.555 |
PPP6C | ITPA | ENSMNEP00000024092 | ENSMNEP00000016008 | Serine/threonine-protein phosphatase. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. | 0.520 |
PPP6C | SRM | ENSMNEP00000024092 | ENSMNEP00000011087 | Serine/threonine-protein phosphatase. | PABS domain-containing protein; Belongs to the spermidine/spermine synthase family. | 0.678 |
PPP6C | TMSB10 | ENSMNEP00000024092 | ENSMNEP00000018336 | Serine/threonine-protein phosphatase. | Thymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family. | 0.694 |
S100A6 | TMSB10 | ENSMNEP00000012561 | ENSMNEP00000018336 | Protein S100; Belongs to the S-100 family. | Thymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family. | 0.448 |
SRM | PPP6C | ENSMNEP00000011087 | ENSMNEP00000024092 | PABS domain-containing protein; Belongs to the spermidine/spermine synthase family. | Serine/threonine-protein phosphatase. | 0.678 |
SRM | TMSB10 | ENSMNEP00000011087 | ENSMNEP00000018336 | PABS domain-containing protein; Belongs to the spermidine/spermine synthase family. | Thymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family. | 0.677 |
ST8SIA4 | TMSB10 | ENSMNEP00000024803 | ENSMNEP00000018336 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4; Belongs to the glycosyltransferase 29 family. | Thymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family. | 0.555 |
TMSB10 | CFL1 | ENSMNEP00000018336 | ENSMNEP00000019840 | Thymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family. | ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. | 0.558 |
TMSB10 | CLASP1 | ENSMNEP00000018336 | ENSMNEP00000043480 | Thymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family. | Cytoplasmic linker associated protein 1. | 0.554 |
TMSB10 | GPNMB | ENSMNEP00000018336 | ENSMNEP00000026716 | Thymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family. | Glycoprotein nmb. | 0.455 |
TMSB10 | IRX6 | ENSMNEP00000018336 | ENSMNEP00000041830 | Thymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family. | Iroquois homeobox 6. | 0.556 |