STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FAT3FAT atypical cadherin 3. (4557 aa)    
Predicted Functional Partners:
FJX1
Four-jointed box kinase 1.
   
 0.952
NCSTN
Nicastrin.
   
 
 0.749
LIX1
Limb and CNS expressed 1.
   
 0.672
LIX1L
Limb and CNS expressed 1 like.
   
 0.672
RBPJL
Recombination signal binding protein for immunoglobulin kappa J region like.
    
 0.669
APH1A
Aph-1 homolog A, gamma-secretase subunit.
     
 0.663
APH1B
Aph-1 homolog B, gamma-secretase subunit.
     
 0.663
PSEN2
Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.
    
  0.663
PSEN1
Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.
    
  0.663
ADAM17
ADAM metallopeptidase domain 17.
     
 0.656
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.