STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ATP8A1Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1164 aa)    
Predicted Functional Partners:
TMEM30A
Cell cycle control protein; Belongs to the CDC50/LEM3 family.
   
 0.993
TMEM30B
Cell cycle control protein; Belongs to the CDC50/LEM3 family.
   
 0.951
LOC105477474
Cell cycle control protein; Belongs to the CDC50/LEM3 family.
   
 0.695
APPL1
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1.
      
 0.582
SLC37A3
Solute carrier family 37 member 3.
     
 0.559
NME8
NME/NM23 family member 8.
    
 0.544
AGAP1
ArfGAP with GTPase domain, ankyrin repeat and PH domain 1.
      
 0.517
RBM48
RNA binding motif protein 48.
      
 0.517
CACNG2
Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
      
 0.516
VTI1B
Vesicle transport through interaction with t-SNAREs 1B.
      
 0.515
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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