node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BTLA | TNFRSF18 | ENSMNEP00000010645 | ENSMNEP00000020055 | B and T lymphocyte associated. | TNF receptor superfamily member 18. | 0.685 |
BTLA | TNFSF14 | ENSMNEP00000010645 | ENSMNEP00000037603 | B and T lymphocyte associated. | TNF superfamily member 14; Belongs to the tumor necrosis factor family. | 0.468 |
CD40LG | FOXP3 | ENSMNEP00000031806 | ENSMNEP00000024682 | CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...] | Forkhead box P3. | 0.694 |
CD40LG | LTA | ENSMNEP00000031806 | ENSMNEP00000032571 | CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...] | Lymphotoxin alpha; Belongs to the tumor necrosis factor family. | 0.745 |
CD40LG | LTB | ENSMNEP00000031806 | ENSMNEP00000013499 | CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...] | Lymphotoxin beta; Belongs to the tumor necrosis factor family. | 0.541 |
CD40LG | TNFRSF18 | ENSMNEP00000031806 | ENSMNEP00000020055 | CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...] | TNF receptor superfamily member 18. | 0.736 |
CD40LG | TNFRSF4 | ENSMNEP00000031806 | ENSMNEP00000038125 | CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...] | TNF receptor superfamily member 4. | 0.508 |
CD40LG | TNFSF11 | ENSMNEP00000031806 | ENSMNEP00000015065 | CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...] | Tumor necrosis factor ligand superfamily member. | 0.580 |
CD40LG | TNFSF14 | ENSMNEP00000031806 | ENSMNEP00000037603 | CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...] | TNF superfamily member 14; Belongs to the tumor necrosis factor family. | 0.536 |
FOXP3 | CD40LG | ENSMNEP00000024682 | ENSMNEP00000031806 | Forkhead box P3. | CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...] | 0.694 |
FOXP3 | TNFRSF18 | ENSMNEP00000024682 | ENSMNEP00000020055 | Forkhead box P3. | TNF receptor superfamily member 18. | 0.567 |
FOXP3 | TNFRSF4 | ENSMNEP00000024682 | ENSMNEP00000038125 | Forkhead box P3. | TNF receptor superfamily member 4. | 0.413 |
LTA | CD40LG | ENSMNEP00000032571 | ENSMNEP00000031806 | Lymphotoxin alpha; Belongs to the tumor necrosis factor family. | CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...] | 0.745 |
LTA | LTB | ENSMNEP00000032571 | ENSMNEP00000013499 | Lymphotoxin alpha; Belongs to the tumor necrosis factor family. | Lymphotoxin beta; Belongs to the tumor necrosis factor family. | 0.989 |
LTA | TNFRSF18 | ENSMNEP00000032571 | ENSMNEP00000020055 | Lymphotoxin alpha; Belongs to the tumor necrosis factor family. | TNF receptor superfamily member 18. | 0.595 |
LTA | TNFSF11 | ENSMNEP00000032571 | ENSMNEP00000015065 | Lymphotoxin alpha; Belongs to the tumor necrosis factor family. | Tumor necrosis factor ligand superfamily member. | 0.596 |
LTA | TNFSF14 | ENSMNEP00000032571 | ENSMNEP00000037603 | Lymphotoxin alpha; Belongs to the tumor necrosis factor family. | TNF superfamily member 14; Belongs to the tumor necrosis factor family. | 0.472 |
LTA | TNFSF15 | ENSMNEP00000032571 | ENSMNEP00000005860 | Lymphotoxin alpha; Belongs to the tumor necrosis factor family. | TNF superfamily member 15. | 0.751 |
LTB | CD40LG | ENSMNEP00000013499 | ENSMNEP00000031806 | Lymphotoxin beta; Belongs to the tumor necrosis factor family. | CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...] | 0.541 |
LTB | LTA | ENSMNEP00000013499 | ENSMNEP00000032571 | Lymphotoxin beta; Belongs to the tumor necrosis factor family. | Lymphotoxin alpha; Belongs to the tumor necrosis factor family. | 0.989 |