STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VPS37CVPS37C subunit of ESCRT-I. (355 aa)    
Predicted Functional Partners:
VPS28
Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.
   
 0.970
TSG101
Tumor susceptibility 101.
    
 0.962
MVB12B
Multivesicular body subunit 12B.
   
 0.959
MVB12A
Multivesicular body subunit 12A.
   
 0.946
CHMP6
Charged multivesicular body protein 6.
     
 0.886
CHMP2A
Charged multivesicular body protein 2A.
    
 0.874
VPS25
Vacuolar protein sorting 25 homolog.
    
 0.873
UBAP1
Ubiquitin associated protein 1.
    
 0.870
SNF8
Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family.
     
 0.867
UEVLD
UEV and lactate/malate dehyrogenase domains.
    
 0.861
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.