STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NPHS2NPHS2 stomatin family member, podocin. (380 aa)    
Predicted Functional Partners:
CD2AP
CD2 associated protein.
   
 
 0.709
TJP1
Tight junction protein 1.
     
 0.689
ANLN
Anillin actin binding protein.
    
 0.679
PODXL
Podocalyxin; Involved in the regulation of both adhesion and cell morphology and cancer progression. Function as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Belongs to the podocalyxin family.
      
 0.660
SYNPO
Synaptopodin.
     
 0.627
TRPC6
Transient receptor potential cation channel subfamily C member 6; Belongs to the transient receptor (TC 1.A.4) family.
    
 
 0.605
NPHS1
NPHS1 adhesion molecule, nephrin.
    
 0.604
CDH3
Cadherin 3; Cadherins are calcium-dependent cell adhesion proteins.
   
 
 0.593
SMPDL3B
Acid sphingomyelinase-like phosphodiesterase; Belongs to the acid sphingomyelinase family.
      
 0.586
KIRREL1
Kirre like nephrin family adhesion molecule 1.
    
 0.581
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.