STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TEKTEK receptor tyrosine kinase. (1124 aa)    
Predicted Functional Partners:
ANGPT2
Angiopoietin 2.
   
 0.989
ANGPT1
Angiopoietin 1.
   
 0.983
ANGPT4
Angiopoietin 4.
   
 0.977
CRK
CRK proto-oncogene, adaptor protein.
    
 0.891
HGF
Hepatocyte growth factor; Belongs to the peptidase S1 family.
     
 0.888
FGF17
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
    
 0.880
VEGFC
Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family.
    
 0.869
SHC2
Uncharacterized protein.
   
 0.862
KITLG
Kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family.
    
 0.859
CRKL
CRK like proto-oncogene, adaptor protein.
    
 0.858
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.