SLAMF1 protein (Macaca nemestrina) - STRING interaction network

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Predicted Interactions

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Score

SLAMF1

Signaling lymphocytic activation molecule family member 1. (356 aa)

Predicted Functional Partners:

SH2D1A

0.937

SLAMF6

0.676

FYN

0.657

CD46

0.637

CD48

0.585

CD4

0.575

SH2D1B

0.565

MYBPH

0.554

MST1R

0.540

CD2

0.531

Your Current Organism:

Macaca nemestrina

NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CD2	CD4	ENSMNEP00000030917	ENSMNEP00000040289	CD2 molecule.	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	0.746
CD2	CD48	ENSMNEP00000030917	ENSMNEP00000041655	CD2 molecule.	CD48 molecule.	0.684
CD2	FYN	ENSMNEP00000030917	ENSMNEP00000008022	CD2 molecule.	Tyrosine-protein kinase.	0.517
CD2	SH2D1A	ENSMNEP00000030917	ENSMNEP00000024303	CD2 molecule.	SH2 domain-containing protein 1A; Cytoplasmic adapter regulating receptors of the signaling lymphocytic activation molecule (SLAM) family such as SLAMF1, CD244, LY9, CD84, SLAMF6 and SLAMF7. In SLAM signaling seems to cooperate with SH2D1B/EAT-2.	0.617
CD2	SLAMF1	ENSMNEP00000030917	ENSMNEP00000025895	CD2 molecule.	Signaling lymphocytic activation molecule family member 1.	0.531
CD2	SLAMF6	ENSMNEP00000030917	ENSMNEP00000040222	CD2 molecule.	SLAM family member 6.	0.530
CD4	CD2	ENSMNEP00000040289	ENSMNEP00000030917	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	CD2 molecule.	0.746
CD4	CD46	ENSMNEP00000040289	ENSMNEP00000006098	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	CD46 molecule.	0.729
CD4	CD48	ENSMNEP00000040289	ENSMNEP00000041655	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	CD48 molecule.	0.654
CD4	FYN	ENSMNEP00000040289	ENSMNEP00000008022	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	Tyrosine-protein kinase.	0.620
CD4	SH2D1A	ENSMNEP00000040289	ENSMNEP00000024303	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	SH2 domain-containing protein 1A; Cytoplasmic adapter regulating receptors of the signaling lymphocytic activation molecule (SLAM) family such as SLAMF1, CD244, LY9, CD84, SLAMF6 and SLAMF7. In SLAM signaling seems to cooperate with SH2D1B/EAT-2.	0.407
CD4	SLAMF1	ENSMNEP00000040289	ENSMNEP00000025895	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	Signaling lymphocytic activation molecule family member 1.	0.575
CD46	CD4	ENSMNEP00000006098	ENSMNEP00000040289	CD46 molecule.	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	0.729
CD46	MYBPH	ENSMNEP00000006098	ENSMNEP00000037276	CD46 molecule.	Myosin binding protein H.	0.554
CD46	SLAMF1	ENSMNEP00000006098	ENSMNEP00000025895	CD46 molecule.	Signaling lymphocytic activation molecule family member 1.	0.637
CD48	CD2	ENSMNEP00000041655	ENSMNEP00000030917	CD48 molecule.	CD2 molecule.	0.684
CD48	CD4	ENSMNEP00000041655	ENSMNEP00000040289	CD48 molecule.	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	0.654
CD48	SH2D1A	ENSMNEP00000041655	ENSMNEP00000024303	CD48 molecule.	SH2 domain-containing protein 1A; Cytoplasmic adapter regulating receptors of the signaling lymphocytic activation molecule (SLAM) family such as SLAMF1, CD244, LY9, CD84, SLAMF6 and SLAMF7. In SLAM signaling seems to cooperate with SH2D1B/EAT-2.	0.672
CD48	SH2D1B	ENSMNEP00000041655	ENSMNEP00000029618	CD48 molecule.	SH2 domain containing 1B.	0.411
CD48	SLAMF1	ENSMNEP00000041655	ENSMNEP00000025895	CD48 molecule.	Signaling lymphocytic activation molecule family member 1.	0.585