node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADSS2 | ENTPD1 | ENSMNEP00000024665 | ENSMNEP00000007859 | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Ectonucleoside triphosphate diphosphohydrolase 1; Belongs to the GDA1/CD39 NTPase family. | 0.995 |
ADSS2 | ENTPD6 | ENSMNEP00000024665 | ENSMNEP00000006762 | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Ectonucleoside triphosphate diphosphohydrolase 6; Belongs to the GDA1/CD39 NTPase family. | 0.995 |
ADSS2 | IMPDH2 | ENSMNEP00000024665 | ENSMNEP00000025922 | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. | 0.998 |
ADSS2 | NT5C | ENSMNEP00000024665 | ENSMNEP00000040762 | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 5', 3'-nucleotidase, cytosolic. | 0.995 |
ADSS2 | NT5C1A | ENSMNEP00000024665 | ENSMNEP00000015823 | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 5'-nucleotidase, cytosolic IA. | 0.996 |
ADSS2 | NT5C1B | ENSMNEP00000024665 | ENSMNEP00000015448 | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Uncharacterized protein. | 0.995 |
ADSS2 | NT5C2 | ENSMNEP00000024665 | ENSMNEP00000027031 | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 5'-nucleotidase, cytosolic II. | 0.995 |
ADSS2 | NT5E | ENSMNEP00000024665 | ENSMNEP00000009936 | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family. | 0.996 |
ENTPD1 | ADSS2 | ENSMNEP00000007859 | ENSMNEP00000024665 | Ectonucleoside triphosphate diphosphohydrolase 1; Belongs to the GDA1/CD39 NTPase family. | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.995 |
ENTPD1 | ENTPD6 | ENSMNEP00000007859 | ENSMNEP00000006762 | Ectonucleoside triphosphate diphosphohydrolase 1; Belongs to the GDA1/CD39 NTPase family. | Ectonucleoside triphosphate diphosphohydrolase 6; Belongs to the GDA1/CD39 NTPase family. | 0.996 |
ENTPD1 | IMPDH2 | ENSMNEP00000007859 | ENSMNEP00000025922 | Ectonucleoside triphosphate diphosphohydrolase 1; Belongs to the GDA1/CD39 NTPase family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. | 0.995 |
ENTPD1 | NT5C | ENSMNEP00000007859 | ENSMNEP00000040762 | Ectonucleoside triphosphate diphosphohydrolase 1; Belongs to the GDA1/CD39 NTPase family. | 5', 3'-nucleotidase, cytosolic. | 0.848 |
ENTPD1 | NT5C1A | ENSMNEP00000007859 | ENSMNEP00000015823 | Ectonucleoside triphosphate diphosphohydrolase 1; Belongs to the GDA1/CD39 NTPase family. | 5'-nucleotidase, cytosolic IA. | 0.848 |
ENTPD1 | NT5C1B | ENSMNEP00000007859 | ENSMNEP00000015448 | Ectonucleoside triphosphate diphosphohydrolase 1; Belongs to the GDA1/CD39 NTPase family. | Uncharacterized protein. | 0.847 |
ENTPD1 | NT5C2 | ENSMNEP00000007859 | ENSMNEP00000027031 | Ectonucleoside triphosphate diphosphohydrolase 1; Belongs to the GDA1/CD39 NTPase family. | 5'-nucleotidase, cytosolic II. | 0.851 |
ENTPD1 | NT5E | ENSMNEP00000007859 | ENSMNEP00000009936 | Ectonucleoside triphosphate diphosphohydrolase 1; Belongs to the GDA1/CD39 NTPase family. | 5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family. | 0.930 |
ENTPD6 | ADSS2 | ENSMNEP00000006762 | ENSMNEP00000024665 | Ectonucleoside triphosphate diphosphohydrolase 6; Belongs to the GDA1/CD39 NTPase family. | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.995 |
ENTPD6 | ENTPD1 | ENSMNEP00000006762 | ENSMNEP00000007859 | Ectonucleoside triphosphate diphosphohydrolase 6; Belongs to the GDA1/CD39 NTPase family. | Ectonucleoside triphosphate diphosphohydrolase 1; Belongs to the GDA1/CD39 NTPase family. | 0.996 |
ENTPD6 | IMPDH2 | ENSMNEP00000006762 | ENSMNEP00000025922 | Ectonucleoside triphosphate diphosphohydrolase 6; Belongs to the GDA1/CD39 NTPase family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. | 0.995 |
ENTPD6 | NT5C1A | ENSMNEP00000006762 | ENSMNEP00000015823 | Ectonucleoside triphosphate diphosphohydrolase 6; Belongs to the GDA1/CD39 NTPase family. | 5'-nucleotidase, cytosolic IA. | 0.860 |