STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TIGITT cell immunoreceptor with Ig and ITIM domains. (312 aa)    
Predicted Functional Partners:
NECTIN2
Nectin cell adhesion molecule 2.
    
 0.995
PVR
PVR cell adhesion molecule.
    
 0.992
NECTIN3
Nectin cell adhesion molecule 3.
    
 0.948
TOMM40L
Translocase of outer mitochondrial membrane 40 like.
    
 0.821
TOMM40
Translocase of outer mitochondrial membrane 40.
    
 0.821
CTLA4
CD152 protein.
   
  
 0.800
LAG3
Lymphocyte activating 3.
   
  
 0.795
CD226
CD226 molecule.
    
 
 0.710
NECTIN1
Nectin cell adhesion molecule 1.
    
 0.697
CD160
CD160 molecule.
   
  
 0.686
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.