STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SETD3Protein-histidine N-methyltransferase. (595 aa)    
Predicted Functional Partners:
ACTA1
Actin alpha 1, skeletal muscle.
    
 
 0.828
ACTG2
Actin gamma 2, smooth muscle.
    
 
 0.828
ACTC1
Actin alpha cardiac muscle 1.
    
 
 0.758
RAB40B
RAB40B, member RAS oncogene family.
   
    0.736
RAB40C
RAB40C, member RAS oncogene family.
   
    0.736
SETD7
Histone-lysine N-methyltransferase SETD7; Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes.
     
 0.700
UTP15
UTP15 small subunit processome component.
   
    0.687
WDR6
WD repeat domain 6.
   
    0.663
SMYD3
SET and MYND domain containing 3.
   
 
 0.662
ACTB
Actin beta.
    
 
 0.655
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.