STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRDM12PR domain zinc finger protein 12; Involved in the positive regulation of histone H3-K9 dimethylation; Belongs to the class V-like SAM-binding methyltransferase superfamily. (363 aa)    
Predicted Functional Partners:
SETD7
Histone-lysine N-methyltransferase SETD7; Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes.
    
 0.527
KMT5A
Lysine methyltransferase 5A.
    
 0.518
KMT2E
Lysine methyltransferase 2E.
     
 0.506
NHLH2
Nescient helix-loop-helix 2.
   
  
 0.504
PIEZO2
Piezo-type mechanosensitive ion channel component.
      
 0.501
DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific.
     
 0.492
CAMKMT
Calmodulin-lysine N-methyltransferase.
     
 0.484
DRGX
Dorsal root ganglia homeobox.
    
 
 0.460
GPR101
G protein-coupled receptor 101; Belongs to the G-protein coupled receptor 1 family.
      
 0.459
EN1
Homeobox protein engrailed-like.
      
 0.418
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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