STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTPN1Tyrosine-protein phosphatase non-receptor type. (435 aa)    
Predicted Functional Partners:
IRS4
Insulin receptor substrate 4.
    
 0.996
INSR
Tyrosine-protein kinase receptor.
   
 0.991
IGF1R
Tyrosine-protein kinase receptor.
   
 0.962
IRS1
Insulin receptor substrate 1.
    
 0.955
CTNNB1
Catenin beta 1.
    
 0.936
IRS2
Insulin receptor substrate 2.
    
 0.936
PTPRF
Protein tyrosine phosphatase receptor type F.
   
0.928
INSRR
Tyrosine-protein kinase receptor.
   
 0.926
EGFR
Receptor protein-tyrosine kinase.
    
 0.921
PTPN11
Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.
   
0.902
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.