STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)    
Predicted Functional Partners:
TNFRSF1A
TNF receptor superfamily member 1A.
    
 0.997
TNFRSF1B
TNF receptor superfamily member 1B.
   
 0.996
TNFAIP3
TNF alpha induced protein 3.
   
 0.979
RIPK1
Receptor interacting serine/threonine kinase 1.
   
 0.978
TRADD
TNFRSF1A associated via death domain.
    
 0.977
IKBKB
Inhibitor of nuclear factor kappa B kinase subunit beta.
   
 0.975
IKBKG
Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.
    
 0.973
TRAF2
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.973
CHUK
Component of inhibitor of nuclear factor kappa B kinase complex.
   
 0.968
TBK1
TANK binding kinase 1.
   
 0.968
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.