STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDKN3Cyclin-dependent kinase inhibitor 3; May play a role in cell cycle regulation. Dual specificity phosphatase active toward substrates containing either phosphotyrosine or phosphoserine residues. (212 aa)    
Predicted Functional Partners:
CDK2
Cyclin dependent kinase 2; Belongs to the protein kinase superfamily.
   
 
 0.954
CDK1
Cyclin dependent kinase 1; Belongs to the protein kinase superfamily.
   
 
 0.933
CDC20
Cell division cycle 20.
   
 0.900
CDK3
Cyclin dependent kinase 3; Belongs to the protein kinase superfamily.
   
 
 0.889
DLGAP5
DLG associated protein 5.
   
  
 0.885
NDC80
NDC80 kinetochore complex component.
   
 
 0.875
NUF2
NUF2 component of NDC80 kinetochore complex.
   
 
 0.875
CCNA2
Cyclin A2; Belongs to the cyclin family.
   
  
 0.868
PRC1
Protein regulator of cytokinesis 1.
   
 
 0.859
TTK
TTK protein kinase.
   
 
 0.854
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.