STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GSDMEGasdermin E. (495 aa)    
Predicted Functional Partners:
GZMA
Granzyme A; Belongs to the peptidase S1 family.
     
 0.622
CASP9
Caspase 9; Belongs to the peptidase C14A family.
  
  
 0.607
GZMB
Granzyme B; Belongs to the peptidase S1 family.
     
 0.605
CTSG
Cathepsin G; Belongs to the peptidase S1 family.
     
 0.604
ENSMNEP00000004019
Uncharacterized protein; Belongs to the peptidase C14A family.
     
 0.597
LOC105492342
Uncharacterized protein; Belongs to the peptidase C14A family.
     
 0.597
ENSMNEP00000041867
Uncharacterized protein; Belongs to the peptidase C14A family.
     
 0.597
GSDMA
Gasdermin A.
      
 0.575
GSDMC
Gasdermin C.
      
 0.555
GSDMD
Gasdermin D.
      
0.479
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.