node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACLY | ATP5F1C | ENSMNEP00000024663 | ENSMNEP00000029744 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | ATP synthase subunit gamma. | 0.769 |
ACLY | CS | ENSMNEP00000024663 | ENSMNEP00000024622 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | Citrate synthase; Belongs to the citrate synthase family. | 0.995 |
ACLY | ENSMNEP00000007551 | ENSMNEP00000024663 | ENSMNEP00000007551 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | Uncharacterized protein. | 0.928 |
ACLY | ENSMNEP00000030369 | ENSMNEP00000024663 | ENSMNEP00000030369 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | Uncharacterized protein. | 0.928 |
ACLY | FH | ENSMNEP00000024663 | ENSMNEP00000014753 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | Fumarate hydratase. | 0.806 |
ACLY | H6PD | ENSMNEP00000024663 | ENSMNEP00000044448 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | Hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase. | 0.568 |
ACLY | MDH2 | ENSMNEP00000024663 | ENSMNEP00000016303 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | Malate dehydrogenase. | 0.967 |
ACLY | SUCLG1 | ENSMNEP00000024663 | ENSMNEP00000012789 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. | 0.988 |
ACLY | URB2 | ENSMNEP00000024663 | ENSMNEP00000030639 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | URB2 ribosome biogenesis homolog. | 0.701 |
ATP5F1C | ACLY | ENSMNEP00000029744 | ENSMNEP00000024663 | ATP synthase subunit gamma. | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | 0.769 |
ATP5F1C | CS | ENSMNEP00000029744 | ENSMNEP00000024622 | ATP synthase subunit gamma. | Citrate synthase; Belongs to the citrate synthase family. | 0.850 |
ATP5F1C | ENSMNEP00000007551 | ENSMNEP00000029744 | ENSMNEP00000007551 | ATP synthase subunit gamma. | Uncharacterized protein. | 0.693 |
ATP5F1C | ENSMNEP00000030369 | ENSMNEP00000029744 | ENSMNEP00000030369 | ATP synthase subunit gamma. | Uncharacterized protein. | 0.693 |
ATP5F1C | FH | ENSMNEP00000029744 | ENSMNEP00000014753 | ATP synthase subunit gamma. | Fumarate hydratase. | 0.887 |
ATP5F1C | H6PD | ENSMNEP00000029744 | ENSMNEP00000044448 | ATP synthase subunit gamma. | Hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase. | 0.618 |
ATP5F1C | MDH2 | ENSMNEP00000029744 | ENSMNEP00000016303 | ATP synthase subunit gamma. | Malate dehydrogenase. | 0.889 |
ATP5F1C | SUCLG1 | ENSMNEP00000029744 | ENSMNEP00000012789 | ATP synthase subunit gamma. | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. | 0.939 |
ATP5F1C | URB2 | ENSMNEP00000029744 | ENSMNEP00000030639 | ATP synthase subunit gamma. | URB2 ribosome biogenesis homolog. | 0.715 |
CS | ACLY | ENSMNEP00000024622 | ENSMNEP00000024663 | Citrate synthase; Belongs to the citrate synthase family. | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | 0.995 |
CS | ATP5F1C | ENSMNEP00000024622 | ENSMNEP00000029744 | Citrate synthase; Belongs to the citrate synthase family. | ATP synthase subunit gamma. | 0.850 |