STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
E2F8E2F transcription factor 8. (867 aa)    
Predicted Functional Partners:
E2F7
E2F transcription factor 7.
  
0.879
FOXM1
Forkhead box M1.
   
  
 0.869
TTK
TTK protein kinase.
   
  
 0.859
BUB1B
Uncharacterized protein.
   
  
 0.858
KIF11
Kinesin family member 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
  
 0.851
NEK2
NIMA related kinase 2.
   
  
 0.841
KIF15
Kinesin family member 15; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
  
 0.840
KIF2C
Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
  
 0.835
TOP2A
DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.
   
  
 0.832
BUB1
BUB1 mitotic checkpoint serine/threonine kinase.
   
  
 0.826
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.