STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TFAP2CTranscription factor AP-2 gamma. (450 aa)    
Predicted Functional Partners:
WWOX
WW domain containing oxidoreductase.
    
 0.920
KCTD1
BTB domain-containing protein.
    
 0.762
KDM5B
Lysine demethylase 5B.
    
 0.727
CITED2
Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2.
    
 0.703
PRDM14
PR/SET domain 14.
    
 
 0.695
MYC
Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes.
   
 0.667
SOX17
SRY-box transcription factor 17.
   
  
 0.660
UBE2I
Ubiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.643
TFAP2A
Transcription factor AP-2 alpha.
  
0.642
ZIC1
Zic family member 1.
    
 
 0.635
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.