STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSMNEP00000038391Uncharacterized protein; Belongs to the FPP/GGPP synthase family. (313 aa)    
Predicted Functional Partners:
MVD
Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes.
  
 0.928
FDFT1
Farnesyl-diphosphate farnesyltransferase 1.
  
 0.923
HMGCS1
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
  
 
 0.907
IDI1
Isopentenyl-diphosphate delta isomerase 1.
  
 
 0.896
ENSMNEP00000042163
Nudix hydrolase domain-containing protein.
  
 
 0.896
GGPS1
Geranylgeranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family.
    
 0.891
DHDDS
Alkyl transferase; Belongs to the UPP synthase family.
  
 
 0.880
RSAD2
Radical S-adenosyl methionine domain containing 2.
     
 0.874
NUS1
NUS1 dehydrodolichyl diphosphate synthase subunit.
  
 
 0.862
FNTB
Protein farnesyltransferase subunit beta; Essential subunit of the farnesyltransferase complex. Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X.
   
 0.856
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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