node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CTH | MVK | ENSMNEP00000002545 | ENSMNEP00000039489 | Cystathionine gamma-lyase. | Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. | 0.900 |
HMGCL | HMGCLL1 | ENSMNEP00000034689 | ENSMNEP00000030977 | 3-hydroxy-3-methylglutaryl-CoA lyase. | 3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1. | 0.875 |
HMGCL | HMGCR | ENSMNEP00000034689 | ENSMNEP00000026728 | 3-hydroxy-3-methylglutaryl-CoA lyase. | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | 0.796 |
HMGCL | HMGCS1 | ENSMNEP00000034689 | ENSMNEP00000010579 | 3-hydroxy-3-methylglutaryl-CoA lyase. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.923 |
HMGCL | HMGCS2 | ENSMNEP00000034689 | ENSMNEP00000027637 | 3-hydroxy-3-methylglutaryl-CoA lyase. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.953 |
HMGCL | MVK | ENSMNEP00000034689 | ENSMNEP00000039489 | 3-hydroxy-3-methylglutaryl-CoA lyase. | Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. | 0.841 |
HMGCLL1 | HMGCL | ENSMNEP00000030977 | ENSMNEP00000034689 | 3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1. | 3-hydroxy-3-methylglutaryl-CoA lyase. | 0.875 |
HMGCLL1 | HMGCR | ENSMNEP00000030977 | ENSMNEP00000026728 | 3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1. | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | 0.796 |
HMGCLL1 | HMGCS1 | ENSMNEP00000030977 | ENSMNEP00000010579 | 3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.922 |
HMGCLL1 | HMGCS2 | ENSMNEP00000030977 | ENSMNEP00000027637 | 3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.922 |
HMGCLL1 | MVK | ENSMNEP00000030977 | ENSMNEP00000039489 | 3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1. | Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. | 0.841 |
HMGCR | HMGCL | ENSMNEP00000026728 | ENSMNEP00000034689 | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | 3-hydroxy-3-methylglutaryl-CoA lyase. | 0.796 |
HMGCR | HMGCLL1 | ENSMNEP00000026728 | ENSMNEP00000030977 | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | 3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1. | 0.796 |
HMGCR | HMGCS1 | ENSMNEP00000026728 | ENSMNEP00000010579 | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.994 |
HMGCR | HMGCS2 | ENSMNEP00000026728 | ENSMNEP00000027637 | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.994 |
HMGCR | MVD | ENSMNEP00000026728 | ENSMNEP00000032834 | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes. | 0.916 |
HMGCR | MVK | ENSMNEP00000026728 | ENSMNEP00000039489 | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. | 0.972 |
HMGCR | PMVK | ENSMNEP00000026728 | ENSMNEP00000004401 | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | Phosphomevalonate kinase. | 0.553 |
HMGCS1 | HMGCL | ENSMNEP00000010579 | ENSMNEP00000034689 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 3-hydroxy-3-methylglutaryl-CoA lyase. | 0.923 |
HMGCS1 | HMGCLL1 | ENSMNEP00000010579 | ENSMNEP00000030977 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1. | 0.922 |