STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
USP14Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (493 aa)    
Predicted Functional Partners:
PSMD12
Proteasome 26S subunit, non-ATPase 12.
   
 0.999
PSMC4
Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family.
   
 0.998
PSMD14
Proteasome 26S subunit, non-ATPase 14.
   
 0.998
PSMD6
Proteasome 26S subunit, non-ATPase 6.
   
 0.997
PSMD11
Proteasome 26S subunit, non-ATPase 11.
   
 0.997
PSMD13
Proteasome 26S subunit, non-ATPase 13.
   
 0.997
PSMD4
Proteasome 26S subunit, non-ATPase 4.
   
 0.997
PSMD1
26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family.
   
 0.996
PSMD3
Proteasome 26S subunit, non-ATPase 3.
   
 0.996
PSMA4
Proteasome endopeptidase complex; Belongs to the peptidase T1A family.
   
 0.994
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.