STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ITSN1Intersectin 1. (1694 aa)    
Predicted Functional Partners:
AP2S1
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
   
 0.994
AP2M1
AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]
    
 0.994
ENSMNEP00000010927
B2-adapt-app_C domain-containing protein.
    
 0.992
AP1B1
AP complex subunit beta.
    
 0.992
AP4B1
AP complex subunit beta; Belongs to the adaptor complexes large subunit family.
    
 0.992
AP2B1
AP complex subunit beta.
    
 0.992
GAS7
Growth arrest specific 7.
   
 0.990
FCHO1
FCH domain only 1.
   
 0.987
NECAP1
NECAP endocytosis associated 1.
    
 0.986
NECAP2
NECAP endocytosis associated 2.
    
 0.986
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.