Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
DM40_112Hypothetical protein. (185 aa)    
Predicted Functional Partners:
DM40_113
Nitrite and sulphite reductase 4Fe-4S domain protein.
 
  
 0.989
DM40_111
Adenylylsulfate reductase, thioredoxin dependent family protein; Reduction of activated sulfate into sulfite.
  
 0.978
DM40_110
Phosphoadenosine phosphosulfate reductase family protein.
  
  
 0.838
cobG
cobG: precorrin-3B synthase.
 
  
 0.826
cysN
Sulfate adenylyltransferase, large subunit; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
  
  
 0.807
cysA
Sulfate ABC transporter, ATP-binding family protein; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system.
  
  
 0.538
cobA
cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase; Belongs to the precorrin methyltransferase family.
  
  
 0.531
DM40_1507
Sulfite exporter TauE/SafE family protein.
 
     0.528
DM40_3867
ABC transporter family protein.
  
  
 0.508
cbl_2
Bacterial regulatory helix-turn-helix, lysR family protein; Belongs to the LysR transcriptional regulatory family.
     
 0.483
Your Current Organism:
Burkholderia cenocepacia
NCBI taxonomy Id: 95486
Other names: ATCC BAA-245, ATCC:BAA:245, B. cenocepacia, Burkholderia cenocepacia Vandamme et al. 2003, Burkholderia cepacia genomovar III, Burkholderia cepacia genomovar IIIb, CCM 4899, CCUG 48434, DSM 16553, LMG 16656, LMG:16656, NCTC 13227
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