Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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DM40_1272ahpC/TSA family protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (168 aa)    
Predicted Functional Partners:
DM40_2671
Glutathione peroxidase family protein; Belongs to the glutathione peroxidase family.
   
 0.944
DM40_3652
Hypothetical protein; Glutathione S-transferase, N-terminal domain protein; Belongs to the GST superfamily.
  
 
  0.935
DM40_3710
Hypothetical protein; Glutathione S-transferase, N-terminal domain protein; Belongs to the GST superfamily.
  
 
  0.932
DM40_5591
Hypothetical protein; Glutathione S-transferase, N-terminal domain protein.
  
 
  0.930
DM40_542
Hypothetical protein; Glutathione S-transferase, N-terminal domain protein.
  
 
  0.929
gor
Glutathione-disulfide reductase; Maintains high levels of reduced glutathione.
 
  
 0.925
DM40_3243
Hypothetical protein; Glutathione S-transferase, N-terminal domain protein.
  
 
  0.917
DM40_3582
Hypothetical protein; Glutathione S-transferase, N-terminal domain protein.
  
 
  0.916
DM40_2876
Glutathione S-transferase.
  
 
  0.915
gshB
Glut_syn: glutathione synthase; Belongs to the prokaryotic GSH synthase family.
     
 0.915
Your Current Organism:
Burkholderia cenocepacia
NCBI taxonomy Id: 95486
Other names: ATCC BAA-245, ATCC:BAA:245, B. cenocepacia, Burkholderia cenocepacia Vandamme et al. 2003, Burkholderia cepacia genomovar III, Burkholderia cepacia genomovar IIIb, CCM 4899, CCUG 48434, DSM 16553, LMG 16656, LMG:16656, NCTC 13227
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