STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hmgAHomogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate. (444 aa)    
Predicted Functional Partners:
hppD
4HPPD: 4-hydroxyphenylpyruvate dioxygenase.
 
 0.999
fahA
Fum_ac_acetase: fumarylacetoacetase.
 
  
 0.998
DM40_4386
glyoxalase/Bleomycin resistance /Dioxygenase superfamily protein.
 
 0.998
DM40_3155
Xylose isomerase-like TIM barrel family protein.
 
 0.997
maiA
maiA: maleylacetoacetate isomerase.
 
 
 0.978
phhA
Phe4hydrox_mono: phenylalanine-4-hydroxylase.
 
  
 0.964
DM40_1997
Hypothetical protein.
 
 0.898
DM40_1483
FAD binding domain protein.
 
  
 0.886
DM40_1484
Hypothetical protein.
 
     0.884
pcbd1
Pterin-4-alpha-carbinolamine dehydratase.
 
  
 0.761
Your Current Organism:
Burkholderia cenocepacia
NCBI taxonomy Id: 95486
Other names: ATCC BAA-245, ATCC:BAA:245, B. cenocepacia, Burkholderia cenocepacia Vandamme et al. 2003, Burkholderia cepacia genomovar III, Burkholderia cepacia genomovar IIIb, CCM 4899, CCUG 48434, DSM 16553, LMG 16656, LMG:16656, NCTC 13227
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